Are B12 Lipotropic Injections Effective for Weight Loss?

Updated on March 30, 2018

B12 Lipotropic Injection Reviews

When an important event is on the horizon, like a wedding, a beach vacation, or a prom, many people feel pressure to shed a few pounds so that they can look their best.

One weight-loss method that is gaining popularity is to use lipotropic shots of B12. "Lipotropic" compounds are those that help catalyse the breakdown of fat during metabolism in the body. While these injections are not new, they are being discussed more among weight watchers of late.

Are they safe? In this article, we’ll look at:

  • What are lipotropic injections or B12-lipo shots?
  • What do the shots contain?
  • Do they work for weight loss?
  • How safe are they?
  • Is it possible to take too much B12?

Do Lipotropic B12 Shots Work for Weight Loss?

"There are no conclusive studies supporting the claim that vitamin B12 aids in weight
loss," says Jackie Arnett Elnahar, a registered dietician in New York City.

Should I Try B12 Shots to Burn Fat?

"Using B12 as a weight loss tool is futile, especially if there is no B12 deficiency," Elnahar says.

Does B12 Boost Energy and Metabolism?

B12 has been correlated with increasing energy for those with a deficiency, says Elnahar. This benefit could give a B12-deficient person the boost they need to exercise.

Do Lipo-B12 Shots Work With Weight-Loss Programs?

Many people with B12 deficiency are most likely to lose weight after getting a B12 injection. According to the Mayo Clinic, people who don't have a deficiency are unlikely to lose weight using this method.

Even for people who benefit from B12 injections, no weight loss diet or pill is sufficient in and by itself. The best results are achieved by a holistic approach to weight-loss.

Lipotropic injections should ideally be supported by:

  • regular exercise
  • a healthy diet
  • avoiding fatty food, liquor, salt, and sugar
  • a positive attitude

Will I Lose Weight by Combining B12 Shots With the HCG Diet?

The Food and Drug Administration (FDA) advises people to avoid the HCG (human chorionic gonadotropin) diet and all products associated with it, many of which are not approved by the FDA.

HCG diets generally fall into the category of "very low calorie diets," which recommend eating as few as 500 calories a day. An average woman needs 2000 calories a day, and an average man needs 2500 calories per day.

Diets that restrict calories this severely can be very dangerous and do not lead to sustainable, healthy weight loss.

What Is in a Lipo-B Shot?

Lipotropic injections, or Lipo-B, contain essential vitamins, minerals, and amino acids that help boost the metabolism.

Providers of Lipo-B injections list the following ingredients:The lipotropic portion of our Lipo B injections is composed of three amino acids:

  • Methionine: This is an important antioxidant and amino acid. It is important for the growth of new blood vessels.
  • Inositol: This is a vitamin-like substance. It improves mood and is used to treat panic disorder, high cholesterol, insomnia, and depression.
  • Choline: Choline is a nutrient that supports energy levels and metabolism.
  • Vitamin B12: Deficiency of B12 (methylcobalamine) can cause fatigue, pale skin, and digestive problems. B12 helps form red blood cells, so without it our bodies don't absorb iron as well, which is why some people with B12 deficiency are anemic. The vitamin also improves our central nervous systems and metabolism.
  • L-Carnitine: Not all Lipo-B injections contain this amino acid, so you should check with your provider. L-Carnitine helps the body produce energy. It is important for heart and brain function, muscle movement, and many other body processes.

Will Vitamin B12 Shots Help Resolve a Deficiency?

"If there is a B12 deficiency," Elnahar says, "a high-quality multivitamin or B12 vitamin would provide the necessary amount of the nutrient."

People who take anti-acid medications, or who are of an older age, when stomach acid gets weaker, should be tested for B12 deficiency.

Benefits of Vitamin B12

B12 is an essential water-soluble vitamin. It plays an important role in red blood cell formation, nerve cell health, and energy production. When we eat protein, vitamin B12 is separated from the food during digestion and is absorbed into the bloodstream. If there isn't adequate acid in the stomach, then the vitamin won't be absorbed properly.

The average daily intake of vitamin B12, as recommended by the Office of Dietary Supplements, is 2.4 micrograms (mcg) for men and women over 14. Pregnant and breastfeeding women require slightly more, at 2.6 mcg and 2.8 mcg, respectively.

Ingredients in a B12 Shot

What it Does
Methionine, inositol and choline
Burns fat
Vitamin B12
Provides energy
Increases metabolism

What Are the Side Effects of B12 Shots?

There are no known risks associated with taking B12 injections.

Some people who take a synthetic form of B12, called cyanocobalamin, experience diarrhea and itching.

Research has not shown any harm from taking excessive amounts of B12. The supplement has a low potential for toxicity.

As with any supplement, you are using them to lose weight, let your doctor know.

Do I Need a Prescription for Lipotroic B12 Shots?

No, but it is recommended that you consult your doctor before using them. For people who are B12 deficient, doctors will typically suggest injections of higher-than-average doses. This type of injection does require a doctor's prescription.

Will B12 Shots Help Treat Megaloblastic Anemia?

Vitamin B12 helps the body develop healthy red blood cells. When there isn't enough B12, red blood cells grow too large, making it difficult for them to pass through the necessary pathways to deliver oxygen.

Megaloblastic anemia is one name for this condition. The most common symptom of this deficiency is fatigue, but weight-loss, shortness of breath, and nausea are other symptoms.

Megaloblastic anemia caused by B12 deficiency is often treated with monthly B12 injections, along with a diet rich in vitamin B12.

Are B12 Shots Used to Treat Pernicious Anemia?

Yes, B12 injections are a common treatment for pernicious anemia, which occurs when the body cannot absorb vitamin B12.

In Summary

  • There are no scientific studies to substantiate weight-loss benefits of B12 injections.
  • Lipotropic injections have been around for a while and no side effects have been reported.
  • It is advisable to consult your physician first.

B12 shots can help:

  • Provide energy boost, if you have a deficiency.
  • Increase metabolism rate.

Effective weight loss strategy

What has been the most effective weight loss strategy for you?

See results

Have You Taken Lipo-B Injections?

What has been your experience with lipotropic injections? Have you or anyone you know has benefits from these shots?

Please leave a comment below, and share your experience with lipo-B injections.

Questions & Answers

    © 2014 Alana Niall


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      • profile image

        Lorilyn 2 months ago

        I got one of these B12/lipo/amino acd shots today and was tired and hungry afterwards, both of which are very unusual for me since I've been following a ketogenic diet. Is that common?

      • 101Ways2Life profile image

        Alana Niall 2 months ago from Christchurch, New Zealand

        Hi Kayla, usually the injections are preferred when the dosage is high, or when the absorption is poor in pills form. It is also used for immediate and local relief. If you are getting the same benefits by having the pills, you may continue to do so.

      • profile image

        Kayla 2 months ago

        So...I looked it up. All of these supplements are available over the counter in pill form. I'm sorry but is taking them in an injection really much better than just taking them orally every day? Sure, your body doesn't absorb them as efficiently, but I feel like it's way less of a hassle to just take a few vitamins.

      • 101Ways2Life profile image

        Alana Niall 3 months ago from Christchurch, New Zealand

        Hi Lee, doctors usually prescribe the shots based on the patient's history and need.

      • profile image

        Lee Ellen Larkin 3 months ago

        What shots are the doctors giving at their office? Is it the same thing advertised here or is it something stronger?

      • 101Ways2Life profile image

        Alana Niall 4 months ago from Christchurch, New Zealand

        Congrats Doris. I am glad to know that my article was useful. Keep at it.

      • profile image

        Doris Turner 4 months ago

        I've taken the B12 and Lipo shot and in the first week, I've lost 6 pounds, no joke. I followed the diet plan, high protein, low carb and implemented exercise at 4 days a week for 40 minutes and I am getting great results. I feel energetic and less pain in my joints. I am going to keep it up until I reach my goal and continue to maintain because it is a lifetime commitment.

      • 101Ways2Life profile image

        Alana Niall 5 months ago from Christchurch, New Zealand

        Hi Laura, please consult your doctor.

      • profile image

        Laura 5 months ago

        I exercise and eat right and have almost reached my goal weight. Being over 50,... I can’t seem to lose the last 15lbs to reach my goal. How many lipotropic injections should I get?

      • profile image

        Terri 7 months ago

        I am on my second shot and I feel no different.

      • profile image

        leticia 8 months ago

        I have been on the b12 an lipo b for a week and I have an itchy throat. Is that normal?

      • profile image

        Marla Scott 9 months ago

        Went to the mall and saw the B12 Store, so I bought a package for myself & my hubby. Had my 1st shot and felt a but dizzy, then full of energy. We went to dinner and I could only eat a small amount. How often should we get the shots?

      • profile image

        Tammy poff 10 months ago

        Can I give these shots my self and without a prescription and where is a reputable place

      • profile image

        anabel cadena 10 months ago

        I've been doing them. on shot #3 no RESULTS

      • profile image

        Angie 10 months ago

        I have a B-12 deficiency and a Vit D deficiency. I started noticing I was extremely tired all the time. Just completely drained even after sleeping a normal amount of hours at night. I thought my B-12 being low might have something to do with it. I went to a clinic and got the B-12 shot but saw where there is a B-12 Lipo shot. I wasn't too sure about it kinda of leary. Tomorrow is my time to get another shot once a week and I'm thinking about doing the Lipo shot that has B-12 in it instead of just the B-12 shot.

      • profile image

        Nutri Lounge 11 months ago

        Interesting read

      • profile image

        christine Boling 13 months ago

        Can someone tell me how to get the shots

      • profile image

        Maria Steyn 13 months ago

        Please where can I order these shots ?

      • profile image

        Welda R Lezcano 15 months ago

        I live in Puerto Rico I'm a nurse and my sister in Florida have used the injection and work wonders. I'm wondering how can I buy the B12 injections by mail. Could you please ltell me know where and how much.

      • profile image

        Niki 15 months ago

        Where do you buy injections if no prescription is needed?

      • profile image

        Shannon 18 months ago

        Do they need to be injected into the muscle?

      • profile image

        Martina 19 months ago

        Where is a good place to buy them online ?

      • profile image

        Tiny7 19 months ago

        @kristi where do you get those at to give to yourself. I think is cheaper doing it that way.

      • profile image

        Maria 19 months ago

        I've tried Liposhots for 5 weeks and gained 10 pounds.

        Exercise and eating healthy was always a daily routine for me. After a knee injury, I gained a few pounds due to inactivity and was hoping to lose faster with Liposhots. I did the opposite for me.

      • profile image

        Kristi 20 months ago

        I give myself 2 Lipo-dbl B12 shots a week for about 4 months and have lost over 30 lbs. This is all under Dr. supervision. They been offering the shots (normally $15) for $10 if you by 12. It's worth it to me!!

      • profile image

        Winnie 20 months ago

        Please where can I get it in nigeria

      • profile image

        Alexis 20 months ago

        Started my first shot of MIC Lipotropic at the B12 store.

        I already feel the energy and I am feeling great. My goal is to drop to 120 pounds. Currently I'm at 165.

        So, starting to eat healthy and drink as much water as possible plus maintaining an active life style.

        I have to go back on Thursday or Friday to get my second shot. After that I can start a weekly regime.

        I hope for the best results.

      • profile image

        Tee 21 months ago

        They don't work well if you're not eating healthy

      • profile image

        Crystal 22 months ago

        I started the shot today. Looking forward to great results. Will let you all know how much i lost in a week. Keeping fingers crossed.

      • profile image

        traci 23 months ago

        I have done these in the past with great results. Two babies later I have decided I needed them again. Lost around 40 lbs last year on my own but I still have 75 lbs to lose. Started them this Tuesday at 205lbs. Today (thursday) I weighed 202!!! Pretty excited! Eating very clean & healthy, going to the gym and wearing my fit bit again to track steps and heart rate and calories burned. Looking forward to my results in 3 months!

      • profile image

        Shirley Engelbrecht 2 years ago

        Where do I buy or order the shots I live in blomefontein free state

      • profile image

        Rhonda 2 years ago

        Can you buy these here in Australia

      • 101Ways2Life profile image

        Alana Niall 2 years ago from Christchurch, New Zealand

        Hi Mei, please consult your doctor.

      • profile image

        Mei 2 years ago

        Hi, I want to try the Mic Lipotropic Complex, Shall I do one or twice a week? And how many ml each time? Thanks

      • profile image

        Elena 2 years ago

        I had injections for six weeks and lost a total of 43 lbs while eating a gluten fee diet.

      • profile image

        Kam 3 years ago

        Has u people experienced any side effects ?

        Please share

      • 101Ways2Life profile image

        Alana Niall 3 years ago from Christchurch, New Zealand

        Hi Ellen, thank you for sharing your positive experience. Losing 13 pounds in 16 days is amazing. It will act as motivation for many readers of this article. You can buy organic ACV from many online shops. Just make sure it is unfiltered, and unpasteurized.

      • profile image

        Ellen 3 years ago

        I have been on them for since 3/24/15 and have lost 13 lbs. (it's 4/10/15) so 16 days and I feel great! I have energy and don't feel so tired and worn out at the end of the work day! But, I would like to purchase this online and give them to myself...anyone know where a safe place to order them from would be?

      • 101Ways2Life profile image

        Alana Niall 3 years ago from Christchurch, New Zealand

        That's great to know Lindy. Thanks for sharing your experience.

      • profile image

        Lindy 3 years ago

        I've been on them since February I have lost 18pds. They def give me energy.

      • 101Ways2Life profile image

        Alana Niall 3 years ago from Christchurch, New Zealand

        Hi Alisha, seek advice of another doctor.

      • 101Ways2Life profile image

        Alana Niall 3 years ago from Christchurch, New Zealand

        Hi Shelley, it is advisable to consult your doctor.

      • profile image

        Porshe 3 years ago

        I started my shot at the last week in February and as of today I've lost 15 lbs lovin it

      • profile image

        Alisha 3 years ago

        My doctor knows nothing about these shots. Can he write me a script and van I get it at a pharmacy?

      • Shelley Taylor profile image

        Shelley Taylor 3 years ago

        Been reading about these for the last few years, eager to try where can I buy. I live in the UK

      • profile image

        Rhonda 3 years ago

        Started the shot last week lost 7lbs. Just had severe pain at the injection site about an hour afterwards that lasted about an hour also very jittery for the same amount of time. Just wondering is this a common side effect. Has anyone else experienced this?

      • profile image

        Kathy 3 years ago

        I have lost 7 pounds after the first week of this shot with the change of watching what I eat. Waiting to see the results for my second week. I hope it continues to work.

      • profile image

        Winnie 3 years ago

        I've been on it for a week and have lost 8lbs! Just got my second shot yesterday! Hope and pray it continues to work!

      • 101Ways2Life profile image

        Alana Niall 3 years ago from Christchurch, New Zealand

        That's an inspirational story Reggie. This is so good to know so that other people can emulate you. Will look forward to further updates from you.

      • profile image

        Reggie 3 years ago

        Started my shots and lost 15 lbs in 3 weeks. Lost another 15 over the next month. From 235 to 205 in less than 2 months but that's not the best part. The best part is I did that back in Aug 14. Today is 3-16-15 and I'm still 205. Just decided to make the push to 195. I post when I make it, not if I make it.

      • profile image

        Tati 3 years ago

        It's been a week for me and i have lost 6lbs. I love it

      • 101Ways2Life profile image

        Alana Niall 3 years ago from Christchurch, New Zealand

        That's an impressive weight loss with ACV, Elizabeth. Thanks for sharing.

      • profile image

        elizabeth 3 years ago

        Ive been on them for 4 weeks and lost 28 lbs in 4 weeks

      • profile image

        Michelle 3 years ago

        I have lost 13 pounds in one week! I have changed my diet as well. I have starting using the lose it app and staying within my calories.

      • profile image

        Norma 3 years ago

        Even if it's only the energy and mental clarity boost of the methycarbolomin, Lipo B is worth every penny!!

      • profile image

        tisha 3 years ago

        Im supposed to go start today I hope it works

      • 101Ways2Life profile image

        Alana Niall 3 years ago from Christchurch, New Zealand

        That's fantastic Yolanda. Glad to now you have amazing results.

      • profile image

        yolanda Cleveland 3 years ago

        Both shot since March 2014 was wearing size 23 I'm now down to a size 14....I feel amazing cause I now eat right and drink now water only now

      • 101Ways2Life profile image

        Alana Niall 3 years ago from Christchurch, New Zealand

        Hi DeTesha, please consult your doctor.

      • profile image

        DaTesha 3 years ago

        Ive been doing them, on shot #5 and have not noticed one thing. No increased energy or weightloss

      • 101Ways2Life profile image

        Alana Niall 3 years ago from Christchurch, New Zealand

        Hi Herbert, that's great to know. All the best.

      • profile image

        herbert hernandez 3 years ago

        Iv been on the shots for 3months lost 40 pounds now im on it again for another 3 months lost 20 pounds got one more month to go I was 360 pounds at one time now im 250 solid muscle . Wow I feel great


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