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Are B12 Lipotropic Injections Effective for Weight Loss?

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B12: the secret to weight loss?

B12: the secret to weight loss?

B12 Lipotropic Injection Reviews

When an important event is on the horizon, like a wedding, a beach vacation, or a prom, many people feel pressure to shed a few pounds so that they can look their best.

One weight-loss method that is gaining popularity is to use lipotropic shots of B12. "Lipotropic" compounds are those that help catalyze the breakdown of fat during metabolism in the body. While these injections are not new, they are being discussed more among weight watchers of late.

Are they safe? In this article, we’ll look at:

  • What are lipotropic injections or B12-lipo shots?
  • What do the shots contain?
  • Do they work for weight loss?
  • How safe are they?
  • Is it possible to take too much B12?
Do the shots work?

Do the shots work?

Do Lipotropic B12 Shots Work for Weight Loss?

"There are no conclusive studies supporting the claim that vitamin B12 aids in weight
loss," says Jackie Arnett Elnahar, a registered dietician in New York City.

Should I Try B12 Shots to Burn Fat?

"Using B12 as a weight loss tool is futile, especially if there is no B12 deficiency," Elnahar says.

Does B12 Boost Energy and Metabolism?

B12 has been correlated with increasing energy for those with a deficiency, says Elnahar. This benefit could give a B12-deficient person the boost they need to exercise.

Do Lipo-B12 Shots Work With Weight-Loss Programs?

Many people with B12 deficiency are most likely to lose weight after getting a B12 injection. According to the Mayo Clinic, people who don't have a deficiency are unlikely to lose weight using this method.

Even for people who benefit from B12 injections, no weight loss diet or pill is sufficient in and by itself. The best results are achieved by a holistic approach to weight loss.

Lipotropic injections should ideally be supported by:

  • regular exercise
  • a healthy diet
  • avoiding fatty food, liquor, salt, and sugar
  • a positive attitude

Will I Lose Weight by Combining B12 Shots With the HCG Diet?

The Food and Drug Administration (FDA) advises people to avoid the HCG (human chorionic gonadotropin) diet and all products associated with it, many of which are not approved by the FDA.

HCG diets generally fall into the category of "very low-calorie diets," which recommend eating as few as 500 calories a day. An average woman needs 2000 calories a day, and an average man needs 2500 calories per day.

Diets that restrict calories this severely can be very dangerous and do not lead to sustainable, healthy weight loss.

What Is in a Lipo-B Shot?

Lipotropic injections, or Lipo-B, contain essential vitamins, minerals, and amino acids that help boost the metabolism.

The lipotropic portion of our Lipo B injections is composed of three amino acids:

  • Methionine: This is an important antioxidant and amino acid. It is important for the growth of new blood vessels.
  • Inositol: This is a vitamin-like substance. It improves mood and is used to treat panic disorder, high cholesterol, insomnia, and depression.
  • Choline: Choline is a nutrient that supports energy levels and metabolism.
  • Vitamin B12: Deficiency of B12 (methylcobalamin) can cause fatigue, pale skin, and digestive problems. B12 helps form red blood cells, so without it our bodies don't absorb iron as well, which is why some people with B12 deficiency are anemic. The vitamin also improves our central nervous systems and metabolism.
  • L-Carnitine: Not all Lipo-B injections contain this amino acid, so you should check with your provider. L-Carnitine helps the body produce energy. It is important for heart and brain function, muscle movement, and many other body processes.

Will Vitamin B12 Shots Help Resolve a Deficiency?

"If there is a B12 deficiency," Elnahar says, "a high-quality multivitamin or B12 vitamin would provide the necessary amount of the nutrient."

People who take anti-acid medications, or who are of older age, when stomach acid gets weaker, should be tested for B12 deficiency.

Benefits of Vitamin B12

B12 is an essential water-soluble vitamin. It plays an important role in red blood cell formation, nerve cell health, and energy production. When we eat protein, vitamin B12 is separated from the food during digestion and is absorbed into the bloodstream. If there isn't adequate acid in the stomach, then the vitamin won't be absorbed properly.

The average daily intake of vitamin B12, as recommended by the Office of Dietary Supplements, is 2.4 micrograms (mcg) for men and women over 14. Pregnant and breastfeeding women require slightly more, at 2.6 mcg and 2.8 mcg, respectively.

Ingredients in a B12 Shot

IngredientWhat it Does

Methionine, inositol and choline

Burns fat

Vitamin B12

Provides energy


Increases metabolism

What Are the Side Effects of B12 Shots?

There are no known risks associated with taking B12 injections.

Some people who take a synthetic form of B12, called cyanocobalamin, experience diarrhea and itching.

Research has not shown any harm from taking excessive amounts of B12. The supplement has a low potential for toxicity.

As with any weight loss supplement, let your doctor know before starting.

Do I Need a Prescription for Lipotroic B12 Shots?

No, but it is recommended that you consult your doctor before using them. For people who are B12 deficient, doctors will typically suggest injections of higher-than-average doses. This type of injection does require a doctor's prescription.

Will B12 Shots Help Treat Megaloblastic Anemia?

Vitamin B12 helps the body develop healthy red blood cells. When there isn't enough B12, red blood cells grow too large, making it difficult for them to pass through the necessary pathways to deliver oxygen.

Megaloblastic anemia is one name for this condition. The most common symptom of this deficiency is fatigue, but weight loss, shortness of breath, and nausea are other symptoms.

Megaloblastic anemia caused by B12 deficiency is often treated with monthly B12 injections, along with a diet rich in vitamin B12.

Are B12 Shots Used to Treat Pernicious Anemia?

Yes, B12 injections are a common treatment for pernicious anemia, which occurs when the body cannot absorb vitamin B12.

In Summary

  • There are no scientific studies to substantiate weight-loss benefits of B12 injections.
  • Lipotropic injections have been around for a while and no side effects have been reported.
  • It is advisable to consult your physician first.

B12 shots can help:

  • Provide an energy boost, if you have a deficiency.
  • Increase metabolism rate.

Effective weight loss strategy

Have You Taken Lipo-B Injections?

What has been your experience with lipotropic injections? Have you or anyone you know benefitted from these shots?

Please leave a comment below, and share your experience with lipo-B injections.

This content is accurate and true to the best of the author’s knowledge and does not substitute for diagnosis, prognosis, treatment, prescription, and/or dietary advice from a licensed health professional. Drugs, supplements, and natural remedies may have dangerous side effects. If pregnant or nursing, consult with a qualified provider on an individual basis. Seek immediate help if you are experiencing a medical emergency.

© 2014 Alana Niall


Nicole on May 23, 2019:

I am taking the B12 shot n it makes me feel super throughout the week. I can surely say it make me feel my best as i do struggle with low iron so in any day my energy level is sloppy

Leticia Moreno on April 26, 2019:

Were can I purchased

SRamos on April 04, 2019:

Where can I purchase the shots

Maria on February 25, 2019:

how can i find in canada toronto

MzTee on August 07, 2018:

why is the dr refering to acv as if that's whats being discussed?

Sophia on August 06, 2018:

I've taken the LipoB12 for 6 weeks. Along with changing my eating habits (no or very little sugar and carbs) and walking 3x a week I went from 164 to currently 149.

Lorilyn on April 18, 2018:

I got one of these B12/lipo/amino acd shots today and was tired and hungry afterwards, both of which are very unusual for me since I've been following a ketogenic diet. Is that common?

Alana Niall (author) from Christchurch, New Zealand on April 09, 2018:

Hi Kayla, usually the injections are preferred when the dosage is high, or when the absorption is poor in pills form. It is also used for immediate and local relief. If you are getting the same benefits by having the pills, you may continue to do so.

Kayla on April 07, 2018:

So...I looked it up. All of these supplements are available over the counter in pill form. I'm sorry but is taking them in an injection really much better than just taking them orally every day? Sure, your body doesn't absorb them as efficiently, but I feel like it's way less of a hassle to just take a few vitamins.

Alana Niall (author) from Christchurch, New Zealand on February 27, 2018:

Hi Lee, doctors usually prescribe the shots based on the patient's history and need.

Lee Ellen Larkin on February 26, 2018:

What shots are the doctors giving at their office? Is it the same thing advertised here or is it something stronger?

Alana Niall (author) from Christchurch, New Zealand on February 17, 2018:

Congrats Doris. I am glad to know that my article was useful. Keep at it.

Doris Turner on February 14, 2018:

I've taken the B12 and Lipo shot and in the first week, I've lost 6 pounds, no joke. I followed the diet plan, high protein, low carb and implemented exercise at 4 days a week for 40 minutes and I am getting great results. I feel energetic and less pain in my joints. I am going to keep it up until I reach my goal and continue to maintain because it is a lifetime commitment.

Alana Niall (author) from Christchurch, New Zealand on January 03, 2018:

Hi Laura, please consult your doctor.

Laura on January 02, 2018:

I exercise and eat right and have almost reached my goal weight. Being over 50,... I can’t seem to lose the last 15lbs to reach my goal. How many lipotropic injections should I get?

Terri on November 17, 2017:

I am on my second shot and I feel no different.

leticia on October 11, 2017:

I have been on the b12 an lipo b for a week and I have an itchy throat. Is that normal?

Marla Scott on September 05, 2017:

Went to the mall and saw the B12 Store, so I bought a package for myself & my hubby. Had my 1st shot and felt a but dizzy, then full of energy. We went to dinner and I could only eat a small amount. How often should we get the shots?

Tammy poff on August 06, 2017:

Can I give these shots my self and without a prescription and where is a reputable place

anabel cadena on August 04, 2017:

I've been doing them. on shot #3 no RESULTS

Angie on July 27, 2017:

I have a B-12 deficiency and a Vit D deficiency. I started noticing I was extremely tired all the time. Just completely drained even after sleeping a normal amount of hours at night. I thought my B-12 being low might have something to do with it. I went to a clinic and got the B-12 shot but saw where there is a B-12 Lipo shot. I wasn't too sure about it kinda of leary. Tomorrow is my time to get another shot once a week and I'm thinking about doing the Lipo shot that has B-12 in it instead of just the B-12 shot.

Nutri Lounge on July 13, 2017:

Interesting read

christine Boling on May 19, 2017:

Can someone tell me how to get the shots

Maria Steyn on May 03, 2017:

Please where can I order these shots ?

Welda R Lezcano on March 05, 2017:

I live in Puerto Rico I'm a nurse and my sister in Florida have used the injection and work wonders. I'm wondering how can I buy the B12 injections by mail. Could you please ltell me know where and how much.

Niki on March 01, 2017:

Where do you buy injections if no prescription is needed?

Shannon on November 30, 2016:

Do they need to be injected into the muscle?

Martina on November 15, 2016:

Where is a good place to buy them online ?

Tiny7 on November 11, 2016:

@kristi where do you get those at to give to yourself. I think is cheaper doing it that way.

Maria on November 08, 2016:

I've tried Liposhots for 5 weeks and gained 10 pounds.

Exercise and eating healthy was always a daily routine for me. After a knee injury, I gained a few pounds due to inactivity and was hoping to lose faster with Liposhots. I did the opposite for me.

Kristi on October 07, 2016:

I give myself 2 Lipo-dbl B12 shots a week for about 4 months and have lost over 30 lbs. This is all under Dr. supervision. They been offering the shots (normally $15) for $10 if you by 12. It's worth it to me!!

Winnie on October 05, 2016:

Please where can I get it in nigeria

Alexis on October 03, 2016:

Started my first shot of MIC Lipotropic at the B12 store.

I already feel the energy and I am feeling great. My goal is to drop to 120 pounds. Currently I'm at 165.

So, starting to eat healthy and drink as much water as possible plus maintaining an active life style.

I have to go back on Thursday or Friday to get my second shot. After that I can start a weekly regime.

I hope for the best results.

Tee on September 01, 2016:

They don't work well if you're not eating healthy

Crystal on August 24, 2016:

I started the shot today. Looking forward to great results. Will let you all know how much i lost in a week. Keeping fingers crossed.

traci on July 14, 2016:

I have done these in the past with great results. Two babies later I have decided I needed them again. Lost around 40 lbs last year on my own but I still have 75 lbs to lose. Started them this Tuesday at 205lbs. Today (thursday) I weighed 202!!! Pretty excited! Eating very clean & healthy, going to the gym and wearing my fit bit again to track steps and heart rate and calories burned. Looking forward to my results in 3 months!

Shirley Engelbrecht on April 21, 2016:

Where do I buy or order the shots I live in blomefontein free state

Rhonda on January 13, 2016:

Can you buy these here in Australia

Alana Niall (author) from Christchurch, New Zealand on August 22, 2015:

Hi Mei, please consult your doctor.

Mei on August 19, 2015:

Hi, I want to try the Mic Lipotropic Complex, Shall I do one or twice a week? And how many ml each time? Thanks

Elena on June 22, 2015:

I had injections for six weeks and lost a total of 43 lbs while eating a gluten fee diet.

Kam on May 26, 2015:

Has u people experienced any side effects ?

Please share

Alana Niall (author) from Christchurch, New Zealand on April 10, 2015:

Hi Ellen, thank you for sharing your positive experience. Losing 13 pounds in 16 days is amazing. It will act as motivation for many readers of this article. You can buy organic ACV from many online shops. Just make sure it is unfiltered, and unpasteurized.

Ellen on April 10, 2015:

I have been on them for since 3/24/15 and have lost 13 lbs. (it's 4/10/15) so 16 days and I feel great! I have energy and don't feel so tired and worn out at the end of the work day! But, I would like to purchase this online and give them to myself...anyone know where a safe place to order them from would be?

Alana Niall (author) from Christchurch, New Zealand on April 01, 2015:

That's great to know Lindy. Thanks for sharing your experience.

Lindy on April 01, 2015:

I've been on them since February I have lost 18pds. They def give me energy.

Alana Niall (author) from Christchurch, New Zealand on March 27, 2015:

Hi Alisha, seek advice of another doctor.

Alana Niall (author) from Christchurch, New Zealand on March 27, 2015:

Hi Shelley, it is advisable to consult your doctor.

Porshe on March 27, 2015:

I started my shot at the last week in February and as of today I've lost 15 lbs lovin it

Alisha on March 26, 2015:

My doctor knows nothing about these shots. Can he write me a script and van I get it at a pharmacy?

Shelley Taylor on March 25, 2015:

Been reading about these for the last few years, eager to try where can I buy. I live in the UK

Rhonda on March 25, 2015:

Started the shot last week lost 7lbs. Just had severe pain at the injection site about an hour afterwards that lasted about an hour also very jittery for the same amount of time. Just wondering is this a common side effect. Has anyone else experienced this?

Kathy on March 23, 2015:

I have lost 7 pounds after the first week of this shot with the change of watching what I eat. Waiting to see the results for my second week. I hope it continues to work.

Winnie on March 18, 2015:

I've been on it for a week and have lost 8lbs! Just got my second shot yesterday! Hope and pray it continues to work!

Alana Niall (author) from Christchurch, New Zealand on March 17, 2015:

That's an inspirational story Reggie. This is so good to know so that other people can emulate you. Will look forward to further updates from you.

Reggie on March 17, 2015:

Started my shots and lost 15 lbs in 3 weeks. Lost another 15 over the next month. From 235 to 205 in less than 2 months but that's not the best part. The best part is I did that back in Aug 14. Today is 3-16-15 and I'm still 205. Just decided to make the push to 195. I post when I make it, not if I make it.

Tati on March 07, 2015:

It's been a week for me and i have lost 6lbs. I love it

Alana Niall (author) from Christchurch, New Zealand on February 15, 2015:

That's an impressive weight loss with ACV, Elizabeth. Thanks for sharing.

elizabeth on February 15, 2015:

Ive been on them for 4 weeks and lost 28 lbs in 4 weeks

Michelle on January 23, 2015:

I have lost 13 pounds in one week! I have changed my diet as well. I have starting using the lose it app and staying within my calories.

Norma on January 17, 2015:

Even if it's only the energy and mental clarity boost of the methycarbolomin, Lipo B is worth every penny!!

tisha on January 12, 2015:

Im supposed to go start today I hope it works

Alana Niall (author) from Christchurch, New Zealand on January 11, 2015:

That's fantastic Yolanda. Glad to now you have amazing results.

yolanda Cleveland on January 09, 2015:

Both shot since March 2014 was wearing size 23 I'm now down to a size 14....I feel amazing cause I now eat right and drink now water only now

Alana Niall (author) from Christchurch, New Zealand on December 31, 2014:

Hi DeTesha, please consult your doctor.

DaTesha on December 22, 2014:

Ive been doing them, on shot #5 and have not noticed one thing. No increased energy or weightloss

Alana Niall (author) from Christchurch, New Zealand on September 08, 2014:

Hi Herbert, that's great to know. All the best.

herbert hernandez on September 08, 2014:

Iv been on the shots for 3months lost 40 pounds now im on it again for another 3 months lost 20 pounds got one more month to go I was 360 pounds at one time now im 250 solid muscle . Wow I feel great